[1] Singh, P., Pandit, S., Mokkapati, V., Garg, A., Ravikumar, V., Mijakovic, I., 2018. Gold nanoparticles in diagnostics and therapeutics for human cancer, International Journal of Molecular Sciences, 19(7), 1979.
https://doi.org/10.3390/ijms19071979
[2] Asghar, M., Sajjad, A., Hanif, S., Ali, J.S., Ali, Z., Zia, M., 2022. Comparative analysis of synthesis, characterization, antimicrobial, antioxidant, and enzyme inhibition potential of roses petal based synthesized copper oxide nanoparticles, Materials Chemistry and Physics, 278, 125724.
https://doi.org/10.1016/j.matchemphys.2021.125724
[3] Zavašnik, J., Šestan, A., Shvalya, V., 2021. Microscopic techniques for the characterisation of metal-based nanoparticles, Comprehensive Analytical Chemistry, 93, Elsevier, 241–284.
https://doi.org/10.1016/bs.coac.2021.01.009
[5] Bhadra, P., Dutta, B., Bhattyacharya, D., Mukherjee, S., 2019. CuO and CuO@SiO2 as a potential antimicrobial and anticancer drug, The Journal of Microbiology, Biotechnology and Food Sciences, 9(1), 63.
https://doi.org/10.15414/jmbfs.2019.9.1.63-66
[6] Abdollahi, Z., Zare, E.N., Salimi, F., Goudarzi, I., Tay, F.R., Makvandi, P., 2021. Bioactive carboxymethyl starch-based hydrogels decorated with CuO nanoparticles: Antioxidant and antimicrobial properties and accelerated wound healing in vivo, International Journal of Molecular Sciences, 22(5), 2531.
https://doi.org/10.3390/ijms22052531
[7] Grigore, M.E., Biscu, E.R., Holban, A.M., Gestal, M.C., Grumezescu, A.M., 2016. Methods of synthesis, properties and biomedical applications of CuO nanoparticles, Pharmaceuticals, 9(4), 75.
https://doi.org/10.3390/ph9040075
[9] Esposito, G., Pastorino, P., Prearo, M., Magara, G., Cesarani, A., Freitas, R., Caldaroni, B., Meloni, D., Pais, A., Dondo, A., Antuofermo, E., Elia, A.C., 2022. Ecotoxicity of copper (I) chloride in grooved carpet shell (Ruditapes decussatus), Antioxidants, 11(11), 2148.
https://doi.org/10.3390/antiox11112148
[10] Georgopoulos, A.R., Yonone-Lioy, M.J., Opiekun, R.E., Lioy, P.J., 2001. Environmental copper: its dynamics and human exposure issues, Journal of Toxicology and Environmental Health Part B: Critical Reviews, 4(4), 341–394.
https://doi.org/10.1080/109374001753146207
[11] Ghaderian, S.M., Ravandi, A.A.G., 2012. Accumulation of copper and other heavy metals by plants growing on Sarcheshmeh copper mining area, Iran, Journal of Geochemical Exploration, 123, 25–32.
https://doi.org/10.1016/j.gexplo.2012.06.022
[12] Rafea, M.A., Roushdy, N., 2008. Determination of the optical band gap for amorphous and nanocrystalline copper oxide thin films prepared by SILAR technique, Journal of Physics D: Applied Physics, 42(1), 015413.
https://doi.org/10.1088/0022-3727/42/1/015413
[13] Mohamed, A.A., Abu-Elghait, M., Ahmed, N.E., Salem, S.S., 2021. Eco-friendly mycogenic synthesis of ZnO and CuO nanoparticles for in vitro antibacterial, antibiofilm, and antifungal applications, Biological Trace Element Research, 199(7), 2788–2799.
https://doi.org/10.1007/s12011-020-02369-4
[14] Jeronsia, J.E., Joseph, L.A., Vinosha, P.A., Mary, A.J., Das, S.J., 2019. Camellia sinensis leaf extract mediated synthesis of copper oxide nanostructures for potential biomedical applications, Materials Today: Proceedings, 8, 214–222.
https://doi.org/10.1016/j.matpr.2019.02.178
[15] Katwal, R., Kaur, H., Sharma, G., Naushad, M., Pathania, D., 2015. Electrochemical synthesized copper oxide nanoparticles for enhanced photocatalytic and antimicrobial activity, Journal of Industrial and Engineering Chemistry, 31, 173–184.
https://doi.org/10.1016/j.jiec.2015.06.021
[16] Aaga, G.F., Anshebo, S.T., 2023. Green synthesis of highly efficient and stable copper oxide nanoparticles using an aqueous seed extract of Moringa stenopetala for sunlight-assisted catalytic degradation of Congo red and alizarin red S, Heliyon, 9(5).
https://doi.org/10.1016/j.heliyon.2023.e15464
[17] Qamar, H., Rehman, S., Chauhan, D.K., Tiwari, A.K., Upmanyu, V., 2020. Green synthesis, characterization and antimicrobial activity of copper oxide nanomaterial derived from Momordica charantia, International Journal of Nanomedicine, 2541–2553.
https://doi.org/10.2147/IJN.S240232
[18] Singh, D., Jain, D., Rajpurohit, D., Jat, G., Kushwaha, H.S., Singh, A., Mohanty, S.R., Al-Sadoon, M.K., Zaman, W., Upadhyay, S.K., 2023. Bacteria assisted green synthesis of copper oxide nanoparticles and their potential applications as antimicrobial agents and plant growth stimulants, Frontiers in Chemistry, 11, 1154128.
https://doi.org/10.3389/fchem.2023.1154128
[19] Sharma, P., Mehta, M., Dhanjal, D.S., Kaur, S., Gupta, G., Singh, H., Thangavelu, L., Rajeshkumar, S., Tambuwala, M., Bakshi, H.A., Chellappan, D.K., Dua, K., Satija, S., 2019. Emerging trends in the novel drug delivery approaches for the treatment of lung cancer, Chemico-Biological Interactions, 309, 108720.
https://doi.org/10.1016/j.cbi.2019.06.033
[20] Applerot, G., Lellouche, J., Lipovsky, A., Nitzan, Y., Lubart, R., Gedanken, A., et al., 2012. Understanding the antibacterial mechanism of CuO nanoparticles: revealing the route of induced oxidative stress, Small, 8(21), 3326–3337.
https://doi.org/10.1002/smll.201200772
[21] Kumar, P.V., Shameem, U., Kollu, P., Kalyani, R., Pammi, S., 2015. Green synthesis of copper oxide nanoparticles using Aloe vera leaf extract and its antibacterial activity against fish bacterial pathogens, BioNanoScience, 5, 135–139.
https://doi.org/10.1007/s12668-015-0177-6
[22] Yugandhar, P., Vasavi, T., Uma Maheswari Devi, P., Savithramma, N., 2017. Bioinspired green synthesis of copper oxide nanoparticles from Syzygium alternifolium (Wt.) Walp: characterization and evaluation of its synergistic antimicrobial and anticancer activity, Applied Nanoscience, 7, 417–427.
https://doi.org/10.1007/s13204-017-0586-4
[23] Sankar, R., Manikandan, P., Malarvizhi, V., Fathima, T., Shivashangari, K.S., Ravikumar, V., 2014. Green synthesis of colloidal copper oxide nanoparticles using Carica papaya and its application in photocatalytic dye degradation, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 121, 746–750.
https://doi.org/10.1016/j.saa.2013.12.061
[24] Bordbar, M., Sharifi-Zarchi, Z., Khodadadi, B., 2017. Green synthesis of copper oxide nanoparticles/clinoptilolite using Rheum palmatum L. root extract: high catalytic activity for reduction of 4-nitro phenol, rhodamine B, and methylene blue, Journal of Sol-Gel Science and Technology, 81, 724–733.
https://doi.org/10.1007/s10971-016-4237-9
[25] Mirhosseini, M., Houshmand Marvasti, S., 2017. Antibacterial activities of copper oxide (CuO) nanoparticles in combination with nisin and ultrasound against foodborne pathogens, Iranian Journal of Medical Microbiology, 11(5), 125–135.
[26] Amjadi, F., Golestani Imani, B., Karimi, F., 2016. Investigation of the effect of copper oxide nanoparticles on the genome of Escherichia coli using RAPD molecular markers, Cellular and Molecular Research (Iranian Journal of Biology), 28(4), 475–487. [in Persian].
[27] Mohammadi, A., Taheri, K., 2024. Microbial synthesis of copper oxide nanoparticles using a new bacterial strain (Bacillus cytotoxicus H2-7) and investigation of different synthesis methods and influencing factors, Microbial Biology, 13(50), 57–79. [in Persian].
[28] Poreddy, R., Engelbrekt, C., Riisager, A., 2015. Copper oxide as efficient catalyst for oxidative dehydrogenation of alcohols with air, Catalysis Science & Technology, 5(4), 2467–2474.
https://doi.org/10.1039/C4CY01548A
[29] Pathak, R., Punetha, V.D., Bhatt, S., Punetha, M., 2024. A review on copper-based nanoparticles as a catalyst: synthesis and applications in coupling reactions, Journal of Materials Science, 59(15), 6169–6205.
https://doi.org/10.1007/s10853-024-09369-2
[30] Kalaivani, P., Mathubala, G., 2024. Biosynthesis of CuO nanoparticles using Coleus aromaticus leaf extract for efficient catalytic applications, Oriental Journal of Chemistry, 40(5).
[31] Amoaghaei, R., Naderi, A., Farhadian, S., 2024. Concentration-dependent effects of copper oxide nanoparticles on osmotic and oxidative stress induced by drought in fennel (Foeniculum vulgare Mill.), Plant Biological Sciences, 15(3), 77–96. [in Persian].
[32] Saleem, M.H., Ejaz, U., Vithanage, M., Bolan, N., Siddique, K.H., 2024. Synthesis, characterization, and advanced sustainable applications of copper oxide nanoparticles: a review, Clean Technologies and Environmental Policy, 1–26.
https://doi.org/10.1007/s10098-024-02719-2
[33] Akhtar, N., Malik, S., Muhammad, F., Ullah, Z., 2025. CuO nanoparticles: tuning properties for energy and optoelectronic applications, Nano Select, e70015.
https://doi.org/10.1002/nano.70015
[34] Baranov, O., Bazaka, K., Belmonte, T., Riccardi, C., Roman, H.E., Mohandas, M., Xu, S., Cvelbar, U., Levchenko, I., 2023. Recent innovations in the technology and applications of low-dimensional CuO nanostructures for sensing, energy and catalysis, Nanoscale Horizons, 8(5), 568–602.
https://doi.org/10.1039/D3NH00105A
[35] Etefagh, R., Azhir, E., Shahtahmasebi, N., 2013. Synthesis of CuO nanoparticles and fabrication of nanostructural layer biosensors for detecting Aspergillus niger fungi, Scientia Iranica, 20(3), 1055–1058.
https://doi.org/10.1016/j.scient.2012.12.031
[36] Ghorbani, M., Tarlani, A., Taghvaei-Ganjali, S., Malekzade, M., 2025. New CuO nanocomposite as non-enzymatic glucose biosensor, Nanomedicine Journal, 12(2).
[37] Guan, P., Li, Y., Zhang, J., Li, W., 2016. Non-enzymatic glucose biosensor based on CuO-decorated CeO2 nanoparticles, Nanomaterials, 6(9), 159.
https://doi.org/10.3390/nano6090159
[38] Ringu, T., Das, A., Ghosh, S., Pramanik, N., 2024. Exploring the potential of copper oxide nanoparticles (CuO NPs) for sustainable environmental bioengineering applications, Nanotechnology for Environmental Engineering, 9(4), 679–707.
https://doi.org/10.1007/s41204-024-00394-3
[39] Singh, J., Kaur, G., Rawat, M., 2016. A brief review on synthesis and characterization of copper oxide nanoparticles and its applications, Journal of Bioelectronics and Nanotechnology, 1(9).
[40] Khayati, G., Nourafkan, E., Karimi, G., Moradgholi, J., 2013. Synthesis of cuprous oxide nanoparticles by mechanochemical oxidation of copper in high planetary energy ball mill, Advanced Powder Technology, 24(1), 301–305.
https://doi.org/10.1016/j.apt.2012.07.003
[41] Yang, B., Chen, D., 2017. Synthesis of CuO nanoparticles for catalytic application via ultrasound-assisted ball milling, Processing and Application of Ceramics, 11(1), 39–44.
https://doi.org/10.2298/PAC1701039Y
[42] Abdulateef, S.A., MatJafri, M., Omar, A., Ahmed, N.M., Azzez, S.A., Ibrahim, I.M., et al., 2016. Preparation of CuO nanoparticles by laser ablation in liquid, AIP Conference Proceedings, AIP Publishing.
[43] Gondal, M., Qahtan, T.F., Dastageer, M.A., Maganda, Y., Anjum, D.H., 2013. Synthesis of Cu/Cu2O nanoparticles by laser ablation in deionized water and their annealing transformation into CuO nanoparticles, Journal of Nanoscience and Nanotechnology, 13(8), 5759–5766.
https://doi.org/10.1166/jnn.2013.7570
[44] Das, A., Kushwaha, A., Bansal, N.R., Suresh, V., Dinda, S., Chattopadhyay, S., et al., 2016. Copper oxide nanoparticles film on glass by using sputter and chemical bath deposition, Advanced Materials Letters, 7(8), 600–603.
https://doi.org/10.5185/amlett.2016.6270
[45] Naz, S., Gul, A., Zia, M., Javed, R., 2023. Synthesis, biomedical applications, and toxicity of CuO nanoparticles, Applied Microbiology and Biotechnology, 107(4), 1039–1061.
https://doi.org/10.1007/s00253-023-12345-6
[46] Thamer, A.A., Imran, S.H., Hassani, R.H., 2025. Sol-Gel process optimization for CuO nanoparticle synthesis achieving high purity and homogeneity, Journal of Physics: Conference Series, IOP Publishing.
[47] Gvozdenko, A.A., Siddiqui, S.A., Blinov, A.V., Golik, A.B., Nagdalian, A.A., Maglakelidze, D.G., Statsenko, E.N., Pirogov, M.A., Blinova, A.A., Sizonenko, M.N., Simonov, A.N., Zhukov, R.B., Kolesnikov, R.O., Ibrahim, S.A., 2022. Synthesis of CuO nanoparticles stabilized with gelatin for potential use in food packaging applications, Scientific Reports, 12(1), 12843.
https://doi.org/10.1038/s41598-022-16843-9
[48] Ali, M.Y., Knight, D., Howlader, M.M., 2023. Nonenzymatic electrochemical glutamate sensor using copper oxide nanomaterials and multiwall carbon nanotubes, Biosensors, 13(2), 237.
https://doi.org/10.3390/bios13020237
[49] Javed, R., Sajjad, A., Naz, S., Sajjad, H., Ao, Q., 2022. Significance of capping agents of colloidal nanoparticles from the perspective of drug and gene delivery, bioimaging, and biosensing: an insight, International Journal of Molecular Sciences, 23(18), 10521.
https://doi.org/10.3390/ijms231810521
[50] Silva, N., Ramírez, S., Díaz, I., Garcia, A., Hassan, N., 2019. Easy, quick, and reproducible sonochemical synthesis of CuO nanoparticles, Materials, 12(5), 804.
https://doi.org/10.3390/ma12050804
[51] Ramanathan, S., Gopinath, S.C., Arshad, M.M., Poopalan, P., Perumal, V., 2021. Nanoparticle synthetic methods: strength and limitations, in Nanoparticles in Analytical and Medical Devices, Elsevier, 31–43.
[52] Gulati, S., Sachdeva, M., Bhasin, K., 2018. Capping agents in nanoparticle synthesis: surfactant and solvent system, AIP Conference Proceedings, AIP Publishing.
[53] Gebreslassie, Y.T., Gebremeskel, F.G., 2024. Green and cost-effective biofabrication of copper oxide nanoparticles: exploring antimicrobial and anticancer applications, Biotechnology Reports, 41, e00828.
https://doi.org/10.1016/j.btre.2024.e00828
[54] Nasrollahzadeh, M., Ghorbannezhad, F., Issaabadi, Z., Sajadi, S.M., 2019. Recent developments in the biosynthesis of Cu-based recyclable nanocatalysts using plant extracts and their application in chemical reactions, The Chemical Record, 19(2–3), 601–643.
https://doi.org/10.1002/tcr.201800123
[55] Ahmad, A., Senapati, S., Khan, M.I., Kumar, R., Sastry, M., 2005. Extra-/intracellular biosynthesis of gold nanoparticles by an alkalotolerant fungus, Trichothecium sp., Journal of Biomedical Nanotechnology, 1(1), 47–53.
https://doi.org/10.1166/jbn.2005.012
[56] Mani, V.M., Kalaivani, S., Sabarathinam, S., Vasuki, M., Soundari, A.J.P.G., Das, M.A., et al., 2021. Copper oxide nanoparticles synthesized from an endophytic fungus Aspergillus terreus: bioactivity and anti-cancer evaluations, Environmental Research, 201, 111502.
https://doi.org/10.1016/j.envres.2021.111502
[57] Bao, C., Jin, M., Lu, R., Zhang, T., Zhao, Y.Y., 2003. Preparation of Au nanoparticles in the presence of low generational poly (amidoamine) dendrimer with surface hydroxyl groups, Materials Chemistry and Physics, 81(1), 160–165.
https://doi.org/10.1016/S0254-0584(03)00144-5
[59] Araújo, I.M., Silva, R.R., Pacheco, G., Lustri, W.R., Tercjak, A., Gutierrez, J., et al., 2018. Hydrothermal synthesis of bacterial cellulose–copper oxide nanocomposites and evaluation of their antimicrobial activity, Carbohydrate Polymers, 179, 341–349.
https://doi.org/10.1016/j.carbpol.2017.09.091
[61] Moroda, M.D., Deressa, T.L., Tiwikrama, A.H., Chala, T.F., 2025. Green synthesis of copper oxide nanoparticles using Rosmarinus officinalis leaf extract and evaluation of its antimicrobial activity, Next Materials, 7, 100337.
[62] Abd El-Halim, M.D., Almehizia, A.A., Elasasy, M.E., Zen, A.A., Kamel, O.M., El-Sayed, A.A., 2025. Larvicidal and adulticidal effect of green synthesis copper oxide nanoparticles using Achillea fragrantissima and its biological and ultra-structural impact on Culex pipiens, Bulletin of the Chemical Society of Ethiopia, 39(3), 535–546.
[63] Seku, K., Reddy, G.B., Koyyala, K.K., Kumar, N.S., AhamadKazi, S., Kumar, N., et al., 2025. Facile and green synthesis of copper oxide nanoparticles using Pithecellobium dulce seed pods and their antioxidant, anticancer, and catalytic applications, Research on Chemical Intermediates, 1–19.
[64] Narasaiah, P., Mandal, B.K., Sarada, N., 2017. Biosynthesis of copper oxide nanoparticles from Drypetes sepiaria leaf extract and their catalytic activity to dye degradation, IOP Conference Series: Materials Science and Engineering, IOP Publishing.
[65] Kalaiyan, G., Topare, N.S., Sikiru, S., Thambidurai, S., Kandasamy, M., Pugazhenthiran, N., et al., 2025. Green synthesis of copper oxide nanoparticles using Euphorbia heterophylla leaf extract for deactivation of pathogenic bacteria and photocatalytic degradation of industrial dyes, Results in Engineering, 26, 104797.
https://doi.org/10.1016/j.rineng.2024.104797
[66] Rostami-Vartooni, A., 2017. Green synthesis of CuO nanoparticles loaded on the seashell surface using Rumex crispus seeds extract and its catalytic applications for reduction of dyes, IET Nanobiotechnology, 11(4), 349–359.
https://doi.org/10.1049/iet-nbt.2016.0102
[67] Vasantharaj, S., Sathiyavimal, S., Bharathi, D., Pannerselvam, B., Jeon, S., Srituravanich, W., 2024. Biosynthesis of copper oxide nanoparticles using Tecoma stans flower extract and its antibacterial, anticancer, and photocatalytic activities, Biocatalysis and Agricultural Biotechnology, 58, 103137.
https://doi.org/10.1016/j.bcab.2024.103137
[68] Yugandhar, P., Vasavi, T., Jayavardhana Rao, Y., Uma Maheswari Devi, P., Narasimha, G., Savithramma, N., 2018. Cost effective, green synthesis of copper oxide nanoparticles using fruit extract of Syzygium alternifolium (Wt.) Walp., characterization and evaluation of antiviral activity, Journal of Cluster Science, 29, 743–755.
https://doi.org/10.1007/s10876-017-1234-5
[69] Jayasimha, H., Chandrappa, K., Sanaulla, P., Dileepkumar, V., 2024. Green synthesis of CuO nanoparticles: a promising material for photocatalysis and electrochemical sensor, Sensors International, 5, 100254.
https://doi.org/10.1016/j.sintl.2024.100254
[70] Ali, S.G., Haseen, U., Jalal, M., Khan, R.A., Alsalme, A., Ahmad, H., et al., 2023. Green synthesis of copper oxide nanoparticles from the leaves of Aegle marmelos and their antimicrobial and photocatalytic activities, Molecules, 28(22), 7499.
https://doi.org/10.3390/molecules28227499
[71] Ogwuegbu, M.C., Ayangbenro, A.S., Mthiyane, D.M., Babalola, O.O., Onwudiwe, D.C., 2024. Green synthesis of CuO nanoparticles using Ligustrum lucidum extract, and the antioxidant and antifungal evaluation, Materials Research Express, 11(5), 055010.
https://doi.org/10.1088/2053-1591/ad4d5f
[72] Orhan, R., 2025. Green synthesis of CuO nanoparticles using Curcuma longa L. extract: composite dielectric and mechanical properties, Materials Testing, (0).
[73] Siddiqui, V.U., Ansari, A., Chauhan, R., Siddiqi, W.A., 2021. Green synthesis of copper oxide (CuO) nanoparticles by Punica granatum peel extract, Materials Today: Proceedings, 36, 751–755.
https://doi.org/10.1016/j.matpr.2020.07.274
[74] Abdollahzadeh, H., Pazhang, Y., Zamani, A., Sharafi, Y., 2024. Green synthesis of copper oxide nanoparticles using walnut shell and their size dependent anticancer effects on breast and colorectal cancer cell lines, Scientific Reports, 14(1), 20323.
https://doi.org/10.1038/s41598-024-20323-7
[75] Thamer, N., Muftin, N., Al-Rubae, S., 2018. Optimization properties and characterization of green synthesis of copper oxide nanoparticles using aqueous extract of Cordia myxa L. leaves, Asian Journal of Chemistry, 30(7), 1559–1563.
[76] Nozari, S., Dehaji Pour Heydarabadi, M., Mahmoudnia, M., 2021. Optimization of biosynthesis of copper oxide nanoparticles using aqueous extract of pistachio (Pistacia vera) leaves, Proceedings of the 12th Iranian Horticultural Science Congress, 1400. [in Persian].
[77] Yadeta Gemachu, L., Lealem Birhanu, A., 2024. Green synthesis of ZnO, CuO and NiO nanoparticles using Neem leaf extract and comparing their photocatalytic activity under solar irradiation, Green Chemistry Letters and Reviews, 17(1), 2293841.
https://doi.org/10.1080/17518253.2023.2293841
[78] Sagadevan, S., Pal, K., Chowdhury, Z.Z., 2017. Fabrication of CuO nanoparticles for structural, optical and dielectric analysis using chemical precipitation method, Journal of Materials Science: Materials in Electronics, 28(17), 12591–12597.
https://doi.org/10.1007/s10854-017-7086-2
[79] Kumar, P., Chaurasia, C.K., Das, S., Bhattacharyya, S., Chakraborty, S., 2023. Synthesis, characterization and application of SiO2 and CuO nanofluid in spray cooling of hot steel plate, Heat and Mass Transfer, 59(8), 1409–1436.
https://doi.org/10.1007/s00231-023-03456-9
[80] Shafiey Dehaj, M., Zamani Mohiabadi, M., 2019. Experimental study of water-based CuO nanofluid flow in heat pipe solar collector, Journal of Thermal Analysis and Calorimetry, 137, 2061–2072.
https://doi.org/10.1007/s10973-019-08039-6
[81] Pourahmad, J., Salami, M., Zarei, M.H., 2023. Comparative toxic effect of bulk copper oxide (CuO) and CuO nanoparticles on human red blood cells, Biological Trace Element Research, 201(1), 149–155.
https://doi.org/10.1007/s12011-022-03206-9
[82] Javid-Naderi, M.J., Sabouri, Z., Jalili, A., Zarrinfar, H., Sammak, S., Darroudi, M., 2025. Green synthesis and characterization of Ag/CuO nanoparticles: exploring their antifungal, antimicrobial, and cytotoxic properties, Environmental Technology & Innovation, 38, 104147.
https://doi.org/10.1016/j.eti.2025.104147
[83] Chaikali, C., Stola, N.D., Lampropoulou, P., Papoulis, D., Lamari, F.N., Orkoula, M., et al., 2025. Green synthesis and comparative analysis of silver, copper oxide, and bimetallic Ag/CuO nanoparticles using Cistus creticus L. extract: physicochemical properties, stability, and antioxidant potential, International Journal of Molecular Sciences, 26(6), 2518.
https://doi.org/10.3390/ijms26062518
[84] Khairy, T., Amin, D.H., Salama, H.M., Elkholy, I.M.A., Elnakib, M., Gebreel, H.M., et al., 2024. Antibacterial activity of green synthesized copper oxide nanoparticles against multidrug-resistant bacteria, Scientific Reports, 14(1), 25020.
https://doi.org/10.1038/s41598-024-25020-7
[85] Beheshtian, A.S., Givianrad, M.H., Rafiee-Pour, H.A., Azar, P.A., 2023. Malva sylvestris mediated synthesis of CuO NPs towards electrochemical determination of quercetin, Optical and Quantum Electronics, 55(5), 463.
https://doi.org/10.1007/s11082-023-04663-9
[86] Khatamifar, M., Fatemi, S.J., 2022. Green synthesis of pure copper oxide nanoparticles using Quercus infectoria galls extract, thermal behavior and their antimicrobial effects, Particulate Science and Technology, 40(1), 18–26.
https://doi.org/10.1080/02726351.2020.1837037
[87] Phang, Y.K., Aminuzzaman, M., Akhtaruzzaman, M., Muhammad, G., Ogawa, S., Watanabe, A., et al., 2021. Green synthesis and characterization of CuO nanoparticles derived from papaya peel extract for the photocatalytic degradation of palm oil mill effluent (POME), Sustainability, 13(2), 796.
https://doi.org/10.3390/su13020796
[88] Shende, S., Ingle, A.P., Gade, A., Rai, M., 2015. Green synthesis of copper nanoparticles by Citrus medica Linn. (Idilimbu) juice and its antimicrobial activity, World Journal of Microbiology and Biotechnology, 31, 865–873.
https://doi.org/10.1007/s11274-015-1831-y
[89] Waris, A., Din, M., Ali, A., Ali, M., Afridi, S., Baset, A., et al., 2021. A comprehensive review of green synthesis of copper oxide nanoparticles and their diverse biomedical applications, Inorganic Chemistry Communications, 123, 108369.
https://doi.org/10.1016/j.inoche.2020.108369
[90] Wang, G., Zhao, K., Gao, C., Wang, J., Mei, Y., Zheng, X., et al., 2021. Green synthesis of copper nanoparticles using green coffee bean and their applications for efficient reduction of organic dyes, Journal of Environmental Chemical Engineering, 9(4), 105331.
https://doi.org/10.1016/j.jece.2021.105331
[91] Ramzan, M., Obodo, R.M., Mukhtar, S., Ilyas, S., Aziz, F., Thovhogi, N., 2021. Green synthesis of copper oxide nanoparticles using Cedrus deodara aqueous extract for antibacterial activity, Materials Today: Proceedings, 36, 576–581.
https://doi.org/10.1016/j.matpr.2020.08.632
[92] Sukumar, S., Rudrasenan, A., Padmanabhan Nambiar, D., 2020. Green-synthesized rice-shaped copper oxide nanoparticles using Caesalpinia bonducella seed extract and their applications, ACS Omega, 5(2), 1040–1051.
https://doi.org/10.1021/acsomega.9b03300
[93] Karunakaran, G., Jagathambal, M., Kumar, G.S., Kolesnikov, E., 2020. Hylotelephium telephium flower extract-mediated biosynthesis of CuO and ZnO nanoparticles with promising antioxidant and antibacterial properties for healthcare applications, JOM, 72(3), 1264–1272.
https://doi.org/10.1007/s11837-019-03956-8
[94] Chandrasekaran, R., Yadav, S.A., Sivaperumal, S., 2020. Phytosynthesis and characterization of copper oxide nanoparticles using the aqueous extract of Beta vulgaris L. and evaluation of their antibacterial and anticancer activities, Journal of Cluster Science, 31(1), 221–230.
https://doi.org/10.1007/s10876-019-01637-2
[95] Gowri, M., Latha, N., Rajan, M., 2019. Copper oxide nanoparticles synthesized using Eupatorium odoratum, Acanthospermum hispidum leaf extracts, and its antibacterial effects against pathogens: a comparative study, BioNanoScience, 9, 545–552.
https://doi.org/10.1007/s12668-019-00621-7
[96] Nagaraj, E., Karuppannan, K., Shanmugam, P., Venugopal, S., 2019. Exploration of bio-synthesized copper oxide nanoparticles using Pterolobium hexapetalum leaf extract by photocatalytic activity and biological evaluations, Journal of Cluster Science, 30, 1157–1168.
https://doi.org/10.1007/s10876-019-01623-8
[97] Kamali, M., Samari, F., Sedaghati, F., 2019. Low-temperature phyto-synthesis of copper oxide nanosheets: its catalytic effect and application for colorimetric sensing, Materials Science and Engineering: C, 103, 109744.
https://doi.org/10.1016/j.msec.2019.109744
[98] Kale, R., Kane, P., Jagtap, P., Sheikh, J., 2019. Citrus limon leaves mediated synthesis method for copper nanoparticles and its structural study, European Journal of Science (EJS).
[99] Salgado, P., Mártire, D.O., Vidal, G., 2019. Eucalyptus extracts-mediated synthesis of metallic and metal oxide nanoparticles: current status and perspectives, Materials Research Express, 6(8), 082006.
https://doi.org/10.1088/2053-1591/ab2a2a
[100] Asemani, M., Anarjan, N., 2019. Green synthesis of copper oxide nanoparticles using Juglans regia leaf extract and assessment of their physico-chemical and biological properties, Green Processing and Synthesis, 8(1), 557–567.
https://doi.org/10.1515/gps-2019-0066[101] Nwanya, A.C., Razanamahandry, L.C., Bashir, A., Ikpo, C.O., Nwanya, S.C., Botha, S., et al., 2019. Industrial textile effluent treatment and antibacterial effectiveness of Zea mays L. dry husk mediated bio-synthesized copper oxide nanoparticles, Journal of Hazardous Materials, 375, 281–289.
https://doi.org/10.1016/j.jhazmat.2019.05.017
[102] Mali, S.C., Raj, S., Trivedi, R., 2019. Biosynthesis of copper oxide nanoparticles using Enicostemma axillare (Lam.) leaf extract, Biochemistry and Biophysics Reports, 20, 100699.
https://doi.org/10.1016/j.bbrep.2019.100699
[103] Hafeez, M., Arshad, R., Khan, J., Akram, B., Ahmad, M.N., Hameed, M.U., et al., 2019. Populus ciliata mediated synthesis of copper oxide nanoparticles for potential biological applications, Materials Research Express, 6(5), 055043.
https://doi.org/10.1088/2053-1591/ab0f7a
[104] Vaidehi, D., Bhuvaneshwari, V., Bharathi, D., Sheetal, B.P., 2018. Antibacterial and photocatalytic activity of copper oxide nanoparticles synthesized using Solanum lycopersicum leaf extract, Materials Research Express, 5(8), 085403.
https://doi.org/10.1088/2053-1591/aad5f3
[107] Sazak, C., Attar, A., Yilmaz, A., Altikatoglu Yapaoz, M., 2023. Biofabrication of Acer palmatum-mediated multifunctional CuO nanoparticles for dye removal, antibacterial–antifungal activity, and molecular docking, ACS Omega, 8(40), 36835–36844.
https://doi.org/10.1021/acsomega.3c04835
[108] Velsankar, K., Vinothini, V., Sudhahar, S., Kumar, M.K., Mohandoss, S., 2020. Green synthesis of CuO nanoparticles via Plectranthus amboinicus leaves extract with its characterization on structural, morphological, and biological properties, Applied Nanoscience, 10, 3953–3971.
https://doi.org/10.1007/s13204-020-01386-9
[109] Eid, A.M., Fouda, A., Hassan, S.E.D., Hamza, M.F., Alharbi, N.K., Elkelish, A., et al., 2023. Plant-based copper oxide nanoparticles; biosynthesis, characterization, antibacterial activity, tanning wastewater treatment, and heavy metals sorption, Catalysts, 13(2), 348.
https://doi.org/10.3390/catal13020348
[110] Priya, M., Venkatesan, R., Deepa, S., Sana, S.S., Arumugam, S., Karami, A.M., et al., 2023. Green synthesis, characterization, antibacterial, and antifungal activity of copper oxide nanoparticles derived from Morinda citrifolia leaf extract, Scientific Reports, 13(1), 18838.
https://doi.org/10.1038/s41598-023-46038-6
[111] Thandapani, G., Arthi, K., Pazhanisamy, P., John, J.J., Vinothini, C., Rekha, V., et al., 2023. Green synthesis of copper oxide nanoparticles using Spinacia oleracea leaf extract and evaluation of biological applications: antioxidant, antibacterial, larvicidal and biosafety assay, Materials Today Communications, 34, 105248.
https://doi.org/10.1016/j.mtcomm.2022.105248
[112] Prabu, P., Losetty, V., 2024. Green synthesis of copper oxide nanoparticles using Macroptilium lathyroides (L.) leaf extract and their spectroscopic characterization, biological activity and photocatalytic dye degradation study, Journal of Molecular Structure, 1301, 137404.
https://doi.org/10.1016/j.molstruc.2023.137404
[113] Rani, A., Asha, S., Mini, M., Rajan, P.P., Tomy, M., Jose, A., et al., 2024. Exploring the antibacterial and antibiofilm potential of copper oxide nanoparticles biosynthesized using Centratherum punctatum leaf extract, South African Journal of Botany, 164, 1–8.
https://doi.org/10.1016/j.sajb.2024.01.002
[114] Nguyen, T.T.T., Nguyen, Y.N.N., Tran, X.T., Nguyen, T.T.T., Van Tran, T., 2023. Green synthesis of CuO, ZnO and CuO/ZnO nanoparticles using Annona glabra leaf extract for antioxidant, antibacterial and photocatalytic activities, Journal of Environmental Chemical Engineering, 11(5), 111003.:
https://doi.org/10.1016/j.jece.2023.111003
[115] Relhan, A., Guleria, S., Bhasin, A., Mirza, A., Zhou, J.L., 2024. Biosynthesized copper oxide nanoparticles by Psidium guajava plants with antibacterial, antidiabetic, antioxidant, and photocatalytic capacity, Biomass Conversion and Biorefinery, 1–18.
https://doi.org/10.1007/s13399-024-04876-9
[116] Khandelwal, M., Choudhary, S., Harish, Kumawat, A., Misra, K.P., Vyas, Y., et al., 2024. An eco-friendly synthesis approach for enhanced photocatalytic and antibacterial properties of copper oxide nanoparticles using Coelastrella terrestris algal extract, International Journal of Nanomedicine, 4137–4162.
https://doi.org/10.2147/IJN.S434567
[117] Ramasubbu, K., Padmanabhan, S., Al-Ghanim, K.A., Nicoletti, M., Govindarajan, M., Sachivkina, N., et al., 2023. Green synthesis of copper oxide nanoparticles using Sesbania grandiflora leaf extract and their evaluation of anti-diabetic, cytotoxic, anti-microbial, and anti-inflammatory properties in an in-vitro approach, Fermentation, 9(4), 332.
https://doi.org/10.3390/fermentation9040332
[118] Saleem, M.H., Ejaz, U., Vithanage, M., Bolan, N., Siddique, K.H., 2024. Synthesis, characterization, and advanced sustainable applications of copper oxide nanoparticles: a review, Clean Technologies and Environmental Policy, 1–26.
https://doi.org/10.1007/s10098-024-02719-2
[119] Modan, E.M., Schiopu, A.G., Moga, S.G., Negrea, D.A., Istrate, D., Ciuca, I., Oproescu, M., 2025. Advanced copper oxide chemical and green synthesis: characterization and antibacterial evaluation, Crystals, 15(1), 7.
https://doi.org/10.3390/cryst15010007
[120] Dhanker, R., Hussain, T., Tyagi, P., Singh, K.J., Kamble, S.S., 2021. The emerging trend of bio-engineering approaches for microbial nanomaterial synthesis and its applications, Frontiers in Microbiology, 12, 638003.
https://doi.org/10.3389/fmicb.2021.638003
[121] Koul, B., Poonia, A.K., Yadav, D., Jin, J.O., 2021. Microbe-mediated biosynthesis of nanoparticles: applications and future prospects, Biomolecules, 11, 886.
https://doi.org/10.3390/biom11060886